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Decellularized intestine retains the capacity to induce neovascularization in the CAM assay. Example photographs of CAM after 7 days postimplantation of a collagen I gel (A, negative control) and decellularized intestine (B). The position of the collagen gel and intestine is highlighted by the dashed circle. Scale bar is 2 mm. (C) Quantification of blood vessels converging toward the implanted material. Error bars are ± SEM. N = 3, p < 0.0001. CAM, chick chorioallantoic membrane.
