FIG. 3.

Micro-CT quantification of bone regeneration in calvarial defects. At 4 and 8 weeks, high-resolution live micro-CT-based quantification and scoring were performed. A score from 0 to 4 was assigned by three independent researchers based on the images attained. For consistent quantification, a 4 mm diameter cylindrical VOI was selected and histomorphometric analyses, including bone volume density and bone mineral density, were performed. (A) Bone Healing Score, (B) Bone Fractional Area, (C) Bone Volume Density, (D) Bone Mineral Density. VOI, volume of interest. *p < 0.05; **p < 0.01. Color images available online at www.liebertpub.com/tea