TABLE 1.

Lymphoproliferative and cytokine responses in mice immunized with PvMSP-1₁₉ and PvMSP-1₄₂

Adjuvant	Antigen	Stimulation index	Concn (pg/ml of supernatant) ofa:
			IL-4	IL-5	INF-γ
CFA	PvMSP-119	12 ± 1.75	39.06 ± 7	148.43 ± 17	2000 ± 186
	PvMSP-142	6.2 ± 0.42	46.81 ± 4	93.7 ± 12	1,400 ± 91
Montanide ISA 720	PvMSP-119	9 ± 1.52	41.66 ± 8	406.20 ± 22	750 ± 89
	PvMSP-142	2.68 ± 0.35	62.50 ± 8	46.3 ± 8	126 ± 11
Alum	PvMSP-119	19 ± 2.42	40.12 ± 6	410.6 ± 19	300 ± 24
	PvMSP-142	11.61 ± 0.64	45.1 ± 5	48.2 ± 9	1,450 ± 86
ASO2A	PvMSP-119	2 ± 0.20	88.01 ± 14	321.45 ± 14	260 ± 17
	PvMSP-142	13.12 ± 0.85	25.0 ± 1.5	77.2 ± 14	250 ± 28
QS21	PvMSP-119	24 ± 2.85	46.87 ± 9	149.20 ± 12	238 ± 11
	PvMSP-142	2.43 ± 0.24	48.29 ± 5.5	184 ± 17	ND
MF59	PvMSP-119	5 ± 0.35	27.34 ± 4	281 ± 15	ND
	PvMSP-142	ND	ND	ND	ND
Control		1 ± 0.5	18 ± 5	42 ± 4	27 ± 9

^aND, not detectable. IL-2 levels were negligible.