. 2004 Oct;72(10):5630–5637. doi: 10.1128/IAI.72.10.5630-5637.2004

TABLE 2.

Patient characteristics at enrollment in age, residence-, and ethnicity-matched severe malaria, mild malaria, and healthy control groups

Characteristic	Severe malaria		Uncomplicated malaria	Healthy control
Characteristic	Survived	Died	Uncomplicated malaria	Healthy control
No. of subjects	230	18	249	251
Female (%)	121 (53)	10 (56)	124 (50)	117 (47)
Age in mo (range)	41.1 (3-162)	29 (8-99)^a	41.5 (6-168)	40.6 (4.5-167)
Hemoglobin concn in g/dl^a (range)	8.89 (2.6-13.5)	6.12 (2.0-11.8)^a	9.5 (5.3-14.2)^b	10.6 (6.2-13.4)^c
WBC/mm³	13,424	16,124	13,338	11,828^c
Parasite density^d	170,029	31,763^a	7,820^b	0^c

Denotes significance at the level of P < 0.05 performed between children that survived and those that died of severe disease. All analyses were performed with paired Student t test.

Paired t test significance (P < 0.05) determined between children with severe and uncomplicated malaria.

Paired t test significance (P < 0.05) determined between children with uncomplicated malaria and healthy. controls.

Data shown are the geometric means. After removal of hyperparasitemic individuals from children with severe disease, the geometric mean parasite density remained significantly elevated over children with uncomplicated disease with a mean parasite density of 34,054 asexual parasites/mm³.