Table I.
Dose level | 131I-tositumomab | Bortezomib | Number treated | DLT |
---|---|---|---|---|
1 | 50 cGy | 0.3 mg/m2 | 2 | 0 |
2 | 75 cGy | 0.3 mg/m2 | 2 | 0 |
3 | 75 cGy | 0.6 mg/m2 | 2 | 0 |
4 | 75 cGy | 0.9 mg/m2 | 8 | 0 |
5 | 75 cGy | 1.2 mg/m2 | 11 | 4 |
DLT, dose limiting toxicity.
Dose level | 131I-tositumomab | Bortezomib | Number treated | DLT |
---|---|---|---|---|
1 | 50 cGy | 0.3 mg/m2 | 2 | 0 |
2 | 75 cGy | 0.3 mg/m2 | 2 | 0 |
3 | 75 cGy | 0.6 mg/m2 | 2 | 0 |
4 | 75 cGy | 0.9 mg/m2 | 8 | 0 |
5 | 75 cGy | 1.2 mg/m2 | 11 | 4 |
DLT, dose limiting toxicity.