TABLE 2.
Invasion of enzyme-treated RBCs by P. falciparum isolates
| Invasion profile type | Isolate | Rate of invasion (%)a of RBCs treated with:
|
||
|---|---|---|---|---|
| Neuraminidase | Trypsin | Chymotrypsin | ||
| 1, NsTsCr | ||||
| 3D7 | 42 ± 9.5 | 34 ± 33 | 74 ± 26 | |
| JSL | 49 ± 18 | 49 ± 22 | 103 ± 20 | |
| ALR | 12 ± 0 | 5 ± 0 | 61 ± 0 | |
| PSS1 | 25 ± 0 | 41 ± 8 | 76 ± 36 | |
| BHZ | 43 ± 12 | 24 ± 3 | 100 ± 36 | |
| 04Q | 30 ± 23 | 38 ± 2 | 81 ± 6 | |
| FFS | 35 ± 2 | 37 ± 2.4 | 121 ± 36 | |
| GVM | 37.5 ± 12.5 | 42 ± 4.5 | 134 ± 18 | |
| 2, NsTrCr | ||||
| Dd2 | 8.6 ± 2.8 | 70 ± 4 | 56 ± 4 | |
| GOS | 3.6 ± 2.8 | 100 ± 30 | 69 ± 10 | |
| LANA | 0 ± 0 | 50 ± 3.5 | 125 ± 17 | |
| NS | 1 ± 1 | 125 ± 27 | 102 ± 16 | |
| IPN | 10.4 ± 3.9 | 63 ± 15 | 78 ± 16 | |
| 35Q | 25 ± 0 | 150 ± 50 | 165 ± 35 | |
| 3, NrTsCr | ||||
| 7G8 | 65 ± 8 | 9 ± 4.6 | 52 ± 11 | |
| 21Q | 77.5 ± 2.5 | 45 ± 5 | 98 ± 17 | |
| 4, NsTsCs | ||||
| RPN | 36 ± 11 | 21 ± 6.5 | 27 ± 1.5 | |
a
Invasion rates are expressed as percentages of invasion of test RBCs relative to invasion of normal RBCs. Data are means±standard deviations. Each experiment was repeated at least three times.