Table 2. Common drug-related problems in pediatric intensive care.
Type of drug-related problems | Number (%) of drug-related problems involved with each medication | |||||
Meropenem | Vancomycin | Piperacillin/tazobactam | Fentanyl | Cefepime | Omeprazole | |
Incompatibility | 6 (4) | 4 (2.70) | 9 (6) | 2 (1.30) | 6 (4) | 2 (1.30) |
High dose | 1 (0.60) | 3 (2) | - | - | - | 3 (2) |
Renal dose adjustment | 1 (0.60) | 1 (0.60) | - | 1 (0.60) | 1 (0.60) | - |
Wrong infusion time | - | 1 (0.60) | - | 3 (2) | - | - |
Low dose | 1 (0.60) | 1 (0.60) | - | 2 (1.30) | - | - |
Therapeutic drug monitoring dose adjustment | - | - | - | - | - | - |
Duplicated drugs | - | - | - | - | - | 1 (0.60) |
Wrong pharmaceutical form | 1 (0.60) | - | - | - | - | 1 (0.60) |
Total (%) | 10 (6.80) | 10 (6.80) | 9 (6) | 8 (5.30) | 7 (4.70) | 7 (4.70) |
Type of drug-related problems | Number (%) of drug-related problems involved with each medication | Other | ||||
Oseltamyvir | Captopril | Methyprednisolone | Phenobarbital | |||
Incompatibility | - | - | 1 (0.60) | - | 24 (17) | |
High dose | - | 1 (0.60) | 3 (2) | 1 (0.60) | 10 (8) | |
Renal dose adjustment | - | 2 (1.30) | - | - | 10 (8) | |
Wrong infusion time | - | - | - | - | 4 (3) | |
Low dose | - | 1 (0.60) | - | - | 7 (5) | |
Therapeutic drug monitoring dose adjustment | - | - | - | 2 (1.30) | 7 (5) | |
Duplicated drugs | - | - | - | - | 4 (3) | |
Wrong pharmaceutical form | 5 (3.30) | - | - | - | 4 (3) | |
Total (%) | 5 (3.30) | 4 (2.70) | 4 (2.70) | 3 (2) | 74 (53) |
Selected drugs accounts for 67 (47%) from 141 drug-related problems (DRP) found by pharmacists. Stability, compatibility and dose were common problems identified by clinical pharmacists. “Others” column refers to drugs that were less common. Only drugs with more than 4 DRPs were reported.