Table 3. Significant SNPs associated with DBP from joint ancestry and association analyses.
Model | UT | SNP | Chr | Closest Gene | Joint posterior |
---|---|---|---|---|---|
Model 1 | N/A | rs77804878 | 7 | MLL3 | 0.99 |
rs114805596 | 7 | MLL3 | 0.99 | ||
rs17173425 | 7 | MLL3 | 0.99 | ||
Model 2 | UT-Self | rs2597955 | 12 | PRH1-PRR4 | 0.99 |
rs2600370 | 12 | PRH1-PRR4 | 1.00 | ||
rs2600368 | 12 | PRH1-PRR4 | 0.99 | ||
rs2708349 | 12 | PRH1-PRR4 | 0.99 | ||
rs2600362 | 12 | PRH1-PRR4 | 0.99 | ||
rs2597921 | 12 | PRH1-PRR4 | 0.99 | ||
rs2416545 | 12 | PRH1-PRR4 | 0.99 | ||
rs2445762 | 15 | CYP19A1 | 0.874 | ||
UT-Other | rs1319603 | 1 | KCNK2/KCTD3 | 0.98 | |
Model 3 - | SNP*UT- | rs11190458 | 10 | PKD2L1 | 0.53 |
UT variable coded as No/Yes | Self | ||||
Model 3 - | SNP*UT- | rs34712049 | 15 | CYP19A1 | 1.00 |
UT-Other coded as Low/High | Other |
Note: joint posterior probability ≥0.5 is considered significant