Table 4. Comparison of the significant genes that we found to be associated with BP with other reported phenotypes.

Model	BP	Effect	Genes	Associated phenotype	Ref.
Model 1	SBP	SNP	LRP8	Triglyceride levels in early onset coronary artery disease	[40]
			CAPN13	BMI in African American girls	[41]
			MITF	Pulmonary hypertension	[42]
			SGCD	Hypertrophic cardiomyopathy	[43]
				HDL-cholesterol	[44]
				Coronary spastic angina	[45]
			MLL3	Regulation of Renin through HOXB9	[46]
	DBP	SNP	MLL3	Regulation of Renin through HOXB9	[46]
Model 2	SBP	UT-Self	SGCD	Hypertrophic cardiomyopathy	[43]
		UT-Other	MITF	Pulmonary hypertension	[42]
			PRH1-PRR4	No known associations
	DBP	UT-Self	CYP19A1	SNP x Sex interactions and cardiovascular disease	[47]
			PRH1-PRR4	No known associations
		UT-Other	KCNK2/KCTD3	Depressive disorders	[48–50]
Model 3	SBP	SNP*UT-Self	PKD2L1	Serum metabolites in African Americans	[51]
UT variable		SNP*UT- Other	ABI3BP	Suicide attempts among patients with depression	[52, 53]
coded as No/Yes			HTR4	Suicide attempts in schizophrenia patients	[51]
			ADRB2	Psychological distress	[54]
			SBF2	Addiction	[55]
			ADM	Anxiety, Depression, and Bi-polar disease	[56]
	DBP	SNP*UT-Self	PKD2L1	Serum metabolites in African Americans	[51]
		SNP*UT-Other	N/A
Model 3	SBP	SNP*UT-Other	CYP19A1	SNP x Sex interactions and cardiovascular disease	[47]
UT variable coded as Low/High	DBP	SNP*UT-Other	CYP19A1	SNP x Sex interactions and cardiovascular disease	[47]

Note: italicized gene names have previously been related to psychological phenotypes