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. 2015 Jun 3;4(6):e31. doi: 10.1038/emi.2015.31

Table 1. Activity of the top 30 active hits that had good activity (better than current clinical drugs) against stationary phase B. burgdorferia.

 

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a

Seven-day-old stationary phase B. burgdorferi culture was treated with drugs or compounds (50 μM) for seven days, at which point the viability of the bacteria was determined, as previously described12.

b

The NSC number is a numeric identifier for substances submitted to the NCI.

c

Residual viable B. burgdorferi was calculated according to the regression equation and the ratio of Green/Red fluorescence obtained by the SYBR Green I/PI assay, as previously described12.

d

Residual viable B. burgdorferi was assayed by epifluorescence microscope counting, as previously described12.