Table 2. Comparison of the MIC values and the activities of some compounds against stationary phase B. burgdorferi.
Antibiotics | MIC (μg/mL) | Activity against stationary phase B. burgdorferi a (%) |
---|---|---|
Doxycycline | ≤0.25 | 77 |
Amoxicillin | ≤0.25 | 77 |
Daptomycin | 12.5–25 | 18 |
Daunomycin 3-oxime | ≤0.36 | 6 |
Daunorubicin | ≤0.35 | 10 |
NSC299187 | 3.26–6.52 | 13 |
Pyronin B | 1.8–3.6 | 19 |
Pyrromycin | 0.37–0.73 | 21 |
Chaetochromin | 2.74–5.47 | 22 |
Prodigiosin | ≤0.2 | 24 |
Mitomycin | ≤0.21 | 25 |
Nanaomycin | 0.76–1.57 | 26 |
Dactinomycin | ≤0.78 | 30 |
Shown as the residual viable cell percentage from epifluorescence microscope counting data.