Fig 5. Invasion of cancer cells with density C(x, t).
The parameters are as in Tables 2 and 3, and χ = 3 × 10−2 cm5g−1day−1. (a) Mutations in both EGFR and MAPK, where λE and λM are increased by 1.15-fold and 1.3-fold, respectively; mutations in both EGFR and AKT, where λE and λA are increased by 1.15-fold and 1.4-fold, respectively; mutations in both MAPK and AKT, where λM and λA are increased by 1.3-fold and 1.4-fold, respectively. (b) Using both anti-miR-21 and anti-miR-155, where both λm1 and λm2 are reduced by a factor 2 compared to the panels in (a). The time is in unit of days, and x is in unit of cm.