Prediction accuracies of meta-predictors made from various combinations of five individual predictors in the (A) D163 and (B) D1679 datasets. The input of ANN in the meta-predictor were preprocessed using preprocess-I transformation. X-axis shows the number of individual predictors in the meta-predictor, while y-axis shows the prediction accuracy (ACC) under three-fold cross validation (A) and five-fold cross validation (B). In the case that x equals to 1, y-axis shows the prediction accuracies of five individual predictors. The numbers of meta-predictors composed of 2, 3, 4, and 5 individual predictors are 10, 10, 5, and 1, respectively.