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. 2016 Dec 21;11(12):e0168899. doi: 10.1371/journal.pone.0168899

Fig 1. Differentially expressed genes (DEG) in cecal tonsils, spleen, and large intestine of the animals that were treated in ovo with prebiotics and synbiotics.

Fig 1

Gene expression was determined by whole-genome microarray GeneChip 1.1 ST (Affymetrix, Santa Clara, CA, US) for four substances injected in ovo. Experimental groups were injected, in ovo, with prebiotics: inulin (P1) and GOS (P2), and synbiotics: inulin with L. lactis subsp. lactis IBB2955 (S1) and GOS with L. lactis subsp. cremoris IBB 477 (S2). The cut-off value was set at 1.66 < FC < 0.66 (FC–fold change). Analysis includes only statistically significant DEG (p-value < 0.05, FDR < 0.1 and). The highest number of DEG was detected in the CT of the P2 group and the lowest in the LI.