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. Author manuscript; available in PMC: 2016 Dec 21.
Published in final edited form as: Mitochondrion. 2015 Sep 25;25:34–37. doi: 10.1016/j.mito.2015.09.002

Fig. 1.

Fig. 1

Mitochondrial bioenergetics and mitochondrial reactive oxygen species (ROS) of peripheral blood mononuclear cells (PBMC) from individuals displaying relative cognitive decline and improvement. (a) Basal rate of PBMCs measured in pMoles consumed oxygen per minute (b) The difference in rate of oxygen consumption before and after treatment of PBMCs with the ATP synthase inhibitor, oligomycin equals the ATP turnover. Rates are expressed as a percentage of the basal rate (c) Reserve respiratory capacity is calculated as the difference between rate of oxygen consumption before and after treatment of PBMCs with the uncoupling agent carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone (FCCP). Rates are expressed as a percentage of the basal rate (d) Mitochondrial ROS in peripheral blood mononuclear cells (PBMC) from individuals displaying relative cognitive decline and improvement.(error-bars indicate SEM).