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. 2004 Sep 18;329(7467):668–673. doi: 10.1136/bmj.329.7467.668

Table 1.

Recent and current clinical trials in pancreatic cancer (further information can be found at www.cancerhelp.org.uk/trials/trials/)

Trial Phase Details Recruitment dates or results
GEM-CAP
III
Single or combination therapy. Comparing gemcitabine alone with a combination of gemcitabine and capecitabine
April 2002 to March 2005
ESPAC 1
III
Compared survival in tumour resected patients having chemoradiotherapy, a combination of chemoradiotherapy and chemotherapy, and no adjuvant treatment
Recently concluded trial showed adjuvant chemotherapy had a significant beneficial effect on survival, whereas chemoradiotherapy had a deleterious effectw13
ESPAC 3 v2
III
Comparing gemcitabine with a combination of fluorouracil and folinic acid
July 2000 to July 2005
MetXia-OB83 and cyclophosphamide I Patients will be given a combination of MetXia-OB83 (gene therapy) and cyclophosphamide March 2004 to October 2005