Table 2.
Enriched GO terms associated with DCGs in breast cancer data from TCGA.
| GO biological process | Total | Observed | Expected | Enrichment | P-value |
|---|---|---|---|---|---|
| cell cycle process (GO:0022402) | 1079 | 100 | 16.46 | 6.07 | 1.12E-45 |
| cell cycle (GO:0007049) | 1311 | 108 | 20 | 5.4 | 3.28E-45 |
| mitotic cell cycle process (GO:1903047) | 741 | 85 | 11.31 | 7.52 | 1.06E-44 |
| mitotic cell cycle (GO:0000278) | 760 | 85 | 11.6 | 7.33 | 7.33E-44 |
| nuclear division (GO:0000280) | 470 | 63 | 7.17 | 8.78 | 1.52E-35 |
| organelle fission (GO:0048285) | 492 | 64 | 7.51 | 8.53 | 1.99E-35 |
| mitotic nuclear division (GO:0007067) | 357 | 56 | 5.45 | 10.28 | 1.34E-34 |
| cell division (GO:0051301) | 477 | 58 | 7.28 | 7.97 | 3.72E-30 |
| chromosome segregation (GO:0007059) | 274 | 46 | 4.18 | 11 | 5.46E-29 |
| sister chromatid segregation (GO:0000819) | 176 | 36 | 2.69 | 13.41 | 7.62E-25 |
| nuclear chromosome segregation (GO:0098813) | 230 | 38 | 3.51 | 10.83 | 3.97E-23 |
| mitotic cell cycle phase transition (GO:0044772) | 249 | 35 | 3.8 | 9.21 | 8.10E-19 |
| mitotic prometaphase (GO:0000236) | 99 | 25 | 1.51 | 16.55 | 1.56E-18 |
| cell cycle phase transition (GO:0044770) | 255 | 35 | 3.89 | 9 | 1.72E-18 |
| regulation of cell cycle (GO:0051726) | 943 | 62 | 14.39 | 4.31 | 2.48E-18 |
| chromosome organization (GO:0051276) | 984 | 63 | 15.01 | 4.2 | 4.15E-18 |
| DNA metabolic process (GO:0006259) | 768 | 52 | 11.72 | 4.44 | 2.67E-15 |
| organelle organization (GO:0006996) | 3133 | 112 | 47.8 | 2.34 | 4.27E-15 |
| mitotic cell cycle phase (GO:0098763) | 211 | 29 | 3.22 | 9.01 | 7.67E-15 |
| cell cycle phase (GO:0022403) | 211 | 29 | 3.22 | 9.01 | 7.67E-15 |
| biological phase (GO:0044848) | 215 | 29 | 3.28 | 8.84 | 1.25E-14 |
| sister chromatid cohesion (GO:0007062) | 113 | 22 | 1.72 | 12.76 | 1.18E-13 |
| cellular resp. to DNA damage stimu. (GO:0006974) | 719 | 48 | 10.97 | 4.38 | 1.27E-13 |
| regulation of cell cycle process (GO:0010564) | 557 | 42 | 8.5 | 4.94 | 2.53E-13 |
| mitotic sister chromatid segregation (GO:0000070) | 90 | 20 | 1.37 | 14.56 | 3.01E-13 |
| cell cycle checkpoint (GO:0000075) | 196 | 25 | 2.99 | 8.36 | 1.09E-11 |
| M phase (GO:0000279) | 173 | 23 | 2.64 | 8.71 | 6.55E-11 |
| mitotic M phase (GO:0000087) | 173 | 23 | 2.64 | 8.71 | 6.55E-11 |
| regulation of mitotic cell cycle (GO:0007346) | 461 | 35 | 7.03 | 4.98 | 1.10E-10 |
| single-organism process (GO:0044699) | 12451 | 253 | 189.98 | 1.33 | 4.67E-10 |
| DNA replication (GO:0006260) | 213 | 24 | 3.25 | 7.38 | 5.74E-10 |
| anaphase (GO:0051322) | 154 | 21 | 2.35 | 8.94 | 6.13E-10 |
| mitotic anaphase (GO:0000090) | 154 | 21 | 2.35 | 8.94 | 6.13E-10 |
| cellular component organization (GO:0016043) | 5133 | 139 | 78.32 | 1.77 | 7.74E-10 |