Table 1. Demographic and clinical characteristics of Crohn's disease patients (n =243) included in the study.
| Total | n =243 |
|---|---|
|
| |
| Females, n (%) | 141 (58) |
|
| |
| Age (years), median (IQR) | 44 (34-56) |
|
| |
| Caucasian ethnicity, n (%) | 235 (96.7) |
|
| |
| BMI (kg/m2), median (IQR) | 25.1 (22.2-28.6) |
|
| |
| Smoking, n (%) | |
| Never | 123 (50.9) |
| Former | 41 (16.9) |
| Current | 78 (32.2) |
|
| |
| Age at diagnosis (years), median (IQR) | 28 (23-38) |
|
| |
| Disease duration (years), median (IQR) | 12 (7-19) |
|
| |
| Disease location (as per Montreal classification (18), n (%) | |
| L1 (ileal) | 57 (23.5) |
| L2 (colonic) | 51 (20.9) |
| L3 (ileocolonic) | 134 (55) |
| L4 (isolated upper digestive) | 1 (0.4) |
|
| |
| Disease behavior (as per Montreal classification (18), n (%) | |
| B1 (non stricturing, non penetrating) | 84 (34.6) |
| B2 (stricturing) | 72 (29.6) |
| B3 (penetrating) | 48 (19.8) |
| P (perianal disease) | 39 (16.1) |
|
| |
| CRS prior to study, n (%) | 175 (72) |
|
| |
| CRS during the study, n (%) | 102 (42) |
|
| |
| Psychiatrics co-morbidities, n (%) | 78 (32) |
|
| |
| LI1, median (IQR) | 8.3 (1.3-12.3) |
|
| |
| LI2, median (IQR) | 8.9 (2.5-20.6) |
|
| |
| DLI, median (IQR) | 0.4 (0-3.8) |
|
| |
| Months between LI1 and LI2, median (IQR) | 48 (42-55) |
|
| |
| 5y SIBDQ, median (IQR) | 50 (40-58) |
|
| |
| 5y HBI, median (IQR) | 4.2 (2-7.2) |
n: number of patients; IQR: interquartile range; BMI: Body Mass Index; CRS: Crohn's disease related surgery (both outpatient and inpatient); LI1: Lémann Index 1; LI2: Lémann index 2; DLI: Delta Lémann Index; SIBDQ: Short inflammatory bowel disease questionnaire; HBI: Harvey Bradshaw Index y: years