Table 4. Determinants of cumulative healthcare expenditure in patients with Crohn's disease based on the multivariate linear regression analysis.
Independent variables | Coefficient | (95% CI) | P value |
---|---|---|---|
Age (y) | -0.007 | -0.013 - -0.001 | 0.029 |
Age at diagnosis (y) | 0.005 | -0.001 – 0.012 | 0.127 |
CRS prior to study | 0.058 | -0.111 – 0.227 | 0.499 |
LI2 | 0.01 | 0.004 – 0.0158 | 0.001 |
DLI | 0.014 | 0.006 – 0.022 | 0.001 |
ESR elevation (/5y) | 0.011 | -0.037 – 0.599 | 0.645 |
CRP elevation (/5y) | 0.023 | -0.033 – 0.080 | 0.412 |
5y SIBDQ | -0.007 | -0.014 - -0.001 | 0.024 |
5y HBI | 0.01 | -0.007 – 0.027 | 0.242 |
Phone calls to IBD clinic | 0.001 | -0.001 – 0.004 | 0.175 |
Psychiatric co-morbidities | 0.068 | -0.072 – 0.209 | 0.335 |
y: years; CRS: Crohn's disease related surgery (both outpatient and inpatient); LI2: Lémann index 2; DLI: Delta Lémann Index; CRP: C-reactive protein; SIBDQ: Short inflammatory bowel disease questionnaire; HBI: Harvey Bradhsaw Index; IBD: Inflammatory bowel disease