. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: Pharm Res. 2016 Sep 15;34(1):73–83. doi: 10.1007/s11095-016-2040-z

Table III.

Conditional stability results for 3 freeze/thaw cycles, time at room temperature (RT) and time post sample extraction. Top row numbers are precision values while the second row is the %difference compared to control samples.

Analyte	Condition	QL	QH
ATP	Freeze/thaw (3×)	2.3	1.8
	Freeze/thaw (3×)	−9.2	−3.0
	RT 6 days	2.6	4.4
	RT 6 days	−12.8	−3.7
	RT 2.5 days	1.4	4.4
	RT 2.5 days	−13.6	−3.7
	Extracted 6 days	1.6	1.1
	Extracted 6 days	0.11	0.01

GTP	Freeze/thaw (3×)	1.3	0.80
	Freeze/thaw (3×)	−9.3	−1.1
	RT 6 days	2.4	3.7
	RT 6 days	−20.6	−0.35
	RT 2.5 days	2.3	3.7
	RT 2.5 days	−16	−0.35
	Extracted 6 days	1.7	0.80
	Extracted 6 days	0.7	−2.1

ITP	Freeze/thaw (3×)	6.7	1.8
	Freeze/thaw (3×)	−7.6	−1.9
	RT 6 days	5.1	3.3
	RT 6 days	−9.9	−0.76
	RT 2.5 days	15.3	3.3
	RT 2.5 days	−10.4	−0.76
	Extracted 6 days	2.8	2.4
	Extracted 6 days	−4.0	−1.5