Skip to main content
. Author manuscript; available in PMC: 2017 Nov 12.
Published in final edited form as: Biofactors. 2016 Jun 21;42(6):703–715. doi: 10.1002/biof.1304

Figure 1. The CXCR3 activating chemokines CXCL9, CXCL10, and CXCL11 are elevated in mouse, rat, and human islets during inflammation.

Figure 1

A. Cxcl9, Cxcl10 and Cxcl11 transcript levels were measured in islets isolated from 10 week old male (n = 4) and female NOD mice (n = 5). Data are expressed relative to age-matched BALB/c control mice (n = 7). **p<0.01, *p<0.05. B–F. Islets from Wistar rats (B, C; n = 4 per group) or human islets (D–F; n =3 per group) were untreated (NT) or stimulated with 10 ng/mL IL-1β, 100 U/mL IFN-γ or both cytokines for 3 h. B–F. Relative mRNA abundance of CXCL9 (B, D), CXCL10 (E) and CXCL11 (C, F) was determined by RT-PCR. ***p<0.001 vs. NT, **p<0.01 vs. NT, *p<0.05 vs. NT.