Table 2.
Baseline Demographic, Laboratory and Risk Behavior Characteristics for AEH Index Cases with Acute or Early HIV infection and Recruited Partners.
| Index Cases |
Recruited Partners |
Both Index Case and Recruited Partner |
p-Value for comparing Index Cases and Recruited Partners* |
|
|---|---|---|---|---|
|
| ||||
| n = 98 | n = 110 | n = 9 | ||
| Demographics | ||||
| Age (median, IQR; n) | 30 (24 – 37; 98) |
32 (26 – 39; 107) |
28 (23 – 39; 9) | 0.17 |
| Male sex (%, n) | 95.9 (93/97) | 95.2 (98/103) | 100.0 (9/9) | > 0.2 |
| Race/ethnicity | > 0.2 | |||
| White non-Hispanic | 58.8 (57/97) | 64.4 (65/101) | 77.8 (7/9) | |
| Black non-Hispanic | 5.2 (5/97) | 5.9 (6/101) | 0 (0/9) | |
| Hispanic | 32.0 (31/97) | 22.8 (23/101) | 0 (0/9) | |
| Other (including
multi- racial) |
4.1 (4/97) | 6.9 (7/101) | 22.2 (2/9) | |
| HIV transmission risk | ||||
| MSM (%, n) | 93.7 (89/95) | 92.2 (94/102) | 100.0 (9/9) | > 0.2 |
| IDU transmission Risk (%, n) | 3.1 (3/98) | 1 (1/100) | 11.1 (1/9) | > 0.2 |
| Laboratory Data at first visit | ||||
| CD4 (cells/μl), (median, IQR;
n) |
504 (378 – 672; 98) |
419(294 – 595; 23) |
543 (390 – 633; 9) | 0.045 |
| VL (HIV-1 RNA log10
copies/ml), (median, IQR; n) |
4.9 (4.0 – 5.6; 98) |
4.7 (3.8 – 5.2; 23) |
5.4 (4.7 – 6.0; 9) | 0.10 |
|
Self-Reported Risk Behavior
in prior 3 months |
||||
| Number of Partners (median, IQR; n) |
2 (1– 5; 85) | 3 (1 – 6; 88) | 5 (3 – 6; 7) | > 0.2 |
| Condom Use RAI (%, n) | > 0.2 | |||
| -Always (100%) | 11.7 (9/77) | 17.3 (9/52) | 33.3 (2/6) | |
| -Usually (50% - 99%) | 29.9 (23/77) | 25.0 (13/52) | 16.7 (1/6) | |
| -Sometimes (1% - 49%) | 20.8 (16/77) | 26.9 (14/52) | 16.7 (1/6) | |
| -Never (0%) | 37.7 (29/77) | 30.8 (16/52) | 33.3 (2/6) | |
| Methamphetamine use, any route (%, n) |
22.9 (8/35) | 21.1 (4/19) | 20 (1/5) | > 0.2 |
| Any drug use, any route † (%,
n) |
36.6 (15/41) | 31.6 (6/19) | 20 (1/5) | > 0.2 |
*
Persons who were both Index Case and Recruited Partner excluded from comparison
†
Excluding alcohol and cannabis
Abbreviations: IDU, injection drug use; IQR, interquartile ratio; MSM, men who have sex with men; RAI, receptive anal intercourse; RPR, rapid plasma regain; VL, viral load