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Outline of our study. i-CT, interim chemotherapy; TPE, total pelvic exenteration; CRM, circumferential resection margin; LPW, lateral pelvic wall; CAPOX, capecitabine plus oxaliplatin; FOLFIRINOX, 5-FU plus irinotecan plus oxaliplatin; FOLFOX, 5-FU plus oxaliplatin; CAPE-OX, capecitabine plus oxaliplatin; AR, anterior resection; APR, abdominal pelvic resections; ISR, intersphincteric resection.
