Table 5. Characteristics of patients by baseline vascular endothelial growth factor-A (VEGF-A) level (n=30).
Characteristic | VEGF-Alo (<57.8 pg/mL) (No., %) | VEGF-Ahi (>57.8 pg/mL) (No., %) | P value |
---|---|---|---|
Lymph node status | 0.43 | ||
uN0 | 6 [40] | 3 [20] | |
uN+ | 9 [60] | 12 [80] | |
R0 resection* | 0.65 | ||
Yes | 10 [71] | 12 [86] | |
No | 4 [29] | 2 [14] | |
pCR*,# | 0.60 | ||
Yes | 3 [28] | 1 [8] | |
No | 11 [72] | 13 [92] |
*, one patient each who was VEGF-Alo and VEGF-Ahi was taken off study for lack of response to induction chemotherapy and are therefore invaluable for surgical outcomes; #, 1 of the 5 patients who achieved a pathologic complete response did not have a baseline VEGF measurement. VEGF, vascular endothelial growth factor.