Uptake of multi-ligand NPs by activated endothelial cells. (I) Uptake of control NPs (PLGA-PEG), GP1b-conjugated NPs (PLGA-PEG-GP1b), and both GP1b and TAT-conjugated NPs (PLGA-PEG-GP1b/TAT) by activated HAECs at static or flow condition (10 dyne/cm2). N=4, *p<0.05. (II) Confocal microscopy images of HAECs uptaken of PLGA-PEG (a), PLGA-PEG-GP1b (b), or PLGA-PEG-GP1b/TAT (c) NPs. Scale bar 20 μm