Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 22;8:315. doi: 10.3389/fnagi.2016.00315

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Rodriguez-Callejas, Fuchs and Perez-Cruz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Double labeling of microglia (iba-1) and tau hyperphosphorylation (AT-100) or conformational change (Alz50) in dentate gyrus. Aged marmoset: Dystrophic microglia presented compact AT100-ir aggregates (blue arrows), but active microglia did not present any AT100-ir (white arrows). In the polymorphic layer dystrophic microglia show Alz50-ir as large cytoplasmic inclusions (blue arrows), whereas in the molecular layer, active microglia (white arrows) do not present any Alz50-ir. A magnification of the polymorphic layer showed dystrophic microglia with fragmented processes and Alz50-ir (^∗), while neighboring cells were not positive for iba-1. Adolescent marmoset: Dystrophic microglia present AT100-ir as diffuse inclusions.