Figure 5.

The sluggish antagonistic center depends on crossover circuitry. (A) The bar graph shows percent of cells requiring specified subfilter for model fit. There was no change in the presence of center subfilters with drug, but the presence of surround subfilter 1 (antagonistic surround) and 2 (center polarity surround) are decreased. (B) Average normalized impulse response for each center subfilter with 3 standard error highlighted by the shaded region (i–iii) and frequency spectrum for each subfilter (iv–vi). Significant difference only present in subfilter 3, with increased tuning after addition of L-AP4 (iii,vi). All comparisons are paired so only cells fit with the specific subfilter under both conditions are compared (n = 95, 94 and 83 for center subfilters 1, 2 and 3, respectively).