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. 2016 Dec 5;5(12):e275. doi: 10.1038/oncsis.2016.72

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Copyright © 2016 The Author(s)

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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hMTH1–hMYH combined depletion significantly increased sub-G1 population. The percentage of sub-G1 population, indicative of cell death, was measured after 96 h of Dox treatment of cells with shRNA set1 (a) and shRNA set2 (b). One representative DAPI histogram is displayed for each condition. Quantified data are shown in bar charts representing mean±s.e.m. from three independent experiments in duplicate. P-values were calculated using one-way analysis of variance (ANOVA). **P<0.01, ***P<0.001, ****P⩽0.0001.