Table 1. Number of actual genotypes and imputed variants in FHS.

	MAF = 0	0 < MAF ≤ 0.01%	0.01% < MAF ≤ 0.5%	0.5% < MAF ≤ 1%	1% < MAF ≤ 5%	MAF > 5%	Total
Genotyped by Affy550K chips	1,578 (0.3%)	0	30,175 (5.6%)	15,171 (2.8%)	60,450 (11.3%)	428,843 (80%)	536,217
Imputed with 1000 G	1,235,417 (4%)	6,834,647 (23%)	11,141,317 (38%)	1,410,031 (5%)	2,799,620 (9%)	6,184,400 (21%)	29,605,432
Imputed with 1000 G + UK10K	3,897,784 (10%)	7,743,094 (20%)	17,568,163 (45%)	1,296,955 (3%)	2,689,779 (7%)	6,193,345 (16%)	39,389,120