Table 2. Proportion of well-imputed variants in FHS imputation results.
MAF |
0 < MAF ≤ 0.01% |
0.01% < MAF ≤ 0.5% |
0.5% < MAF ≤ 1% |
1% < MAF ≤ 5% |
MAF > 5% |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Reference panel | 1000 G | 1000 G + UK10K | 1000 G | 1000 G + UK10K | 1000 G | 1000 G + UK10K | 1000 G | 1000 G + UK10K | 1000 G | 1000 G + UK10K | |
Total imputed variants | 6,834,647 | 7,743,094 | 11,141,317 | 17,568,163 | 1,410,031 | 1,296,955 | 2,799,620 | 2,689,779 | 6,184,400 | 6,193,345 | |
INFO | ≥0.4 | 12.0% | 21.2% | 62.9% | 76.1% | 90.8% | 98.4% | 97.1% | 99.2% | 99.3% | 99.8% |
≥0.5 | 9.0% | 17.9% | 46.4% | 62.1% | 74.5% | 94.3% | 89.3% | 97.7% | 97.8% | 99.4% | |
≥0.6 | 4.9% | 15.1% | 33.0% | 46.0% | 55.7% | 83.2% | 77.3% | 93.2% | 95.0% | 98.4% | |
≥0.7 | 0.0% | 11.6% | 22.5% | 31.4% | 38.8% | 64.2% | 64.2% | 83.4% | 91.0% | 96.4% | |
≥0.8 | 0.0% | 7.4% | 13.4% | 19.5% | 25.0% | 41.9% | 51.0% | 67.8% | 85.0% | 92.2% | |
≥0.9 | 0.0% | 3.6% | 5.2% | 10.1% | 14.1% | 23.0% | 36.9% | 48.8% | 73.9% | 83.5% |
The imputations were performed with 1000 G and 1000 G + UK10K reference panels.