Table 4. Multivariate Cox Survival Analysis Based on FT3 Level and Presence of LGE.
| Model 1* |
Model 2† |
Model 3‡ |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (per 5 years) | 1.073 | 1.056–1.983 | 0.040 | 1.094 | 1.059–1.351 | 0.043 | 1.090 | 1.012–1.341 | 0.035 |
| Gender (male) | 1.629 | 0.968–2.217 | 0.091 | 1.492 | 0.453–2.381 | 0.136 | |||
| LVEF (per 5%) | 0.754 | 0.613–0.992 | 0.026 | 0.781 | 0.539–0.974 | 0.035 | 0.746 | 0.609–0.935 | 0.029 |
| Anemia | 3.712 | 1.203–10.020 | 0.049 | 3.519 | 1.197–8.356 | 0.022 | |||
| Renal Dysfunction | 2.642 | 1.136–4.184 | 0.039 | 2.216 | 0.972–3.923 | 0.065 | |||
| FT3 < 2.77 | 2.181 | 1.627–7.589 | 0.020 | ||||||
| Presence of LGE | 5.489 | 1.451–10.76 | 0.012 | ||||||
| LGE-negtive+ FT3 < 2.77 | 2.127 | 0.830–5.107 | 0.145 | ||||||
| LGE-positive+ FT3 ≥ 2.77 | 5.490 | 2.645–9.823 | 0.011 | 4.966 | 1.851–8.658 | 0.007 | |||
| LGE-positive+ FT3 < 2.77 | 7.908 | 2.433–14.908 | 0.002 | 8.623 | 3.626–16.438 | 0.001 | |||
*Multivariate Cox model selected by a stepwise method with factors that were significant in the univariate analysis and established risk factors for prognosis (age, gender, NYHA classification).
†Model with the combination of LGE and FT3 < 2.77, adjusted for predictors selected by Model 1.
‡Best predictive model in which predictors with P value < 0.1 were kept, adjusted for significant predictors selected by a stepwise Cox regression analysis based on Models 1 and 2.