Figure 3. The LOO validation and n-fold cross-validations were performed for seven HATs including CREBBP, EP300, HAT1, KAT2A, KAT2B, KAT5 and KAT8.

The known human HAT-specific sites were used for training. Due to the data limitation, only 4- and 6-fold cross-validations were carried out for HAT1 and KAT8. AROC values of the LOO validation and n-fold cross-validations were calculated.