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. 2016 Dec 22;6:38846. doi: 10.1038/srep38846

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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EPR spectra of 5-PCSL (A) and 14-PCSL (B) in lipid bilayers composed of DOPC or DOPC and CUR, in the absence and in the presence of Aβ(25–35). Red lines are guides for the eye, highlighting the shifts of the low-field maximum and high-field minimum. Increase in outer hyperfine splitting of 5-PCSL and 14-PCSL in DOPC, DOPG and DOPC/DOPG 90/10 bilayers upon inclusion of ligands (CUR, DMC, BDMC, MIX, CYC, THC, HHC and OHC) in the lipid formulation (panels C,E) and upon addition of Aβ(25/35) to the system (panels D,F).