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. 2016 Dec 22;6:39585. doi: 10.1038/srep39585

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Copyright © 2016, The Author(s)

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(A) Representative Kir2.1 currents elicited by voltage steps starting from a holding potential of 0 mV, under control (static) and fluid-flow conditions in a high-extracellular-K⁺ solution. (B) Representative tracing of IKir2.1 at −100 mV before and after fluid-flow application. (C) Average current-voltage (I–V) relationships in the absence and presence of fluid flow (n = 8); *p < 0.05, **p < 0.01, ***p < 0.001 vs control. (D) Fluid-flow-induced percentage increase in current at different voltage steps; n.s., no significant difference between the indicated voltages (as assessed by one-way analysis of variance [ANOVA]).