Table 1. Localization and potential roles of extra-hypothalamic kisspeptin.
Brain area/Organ | Species | Potential roles of kisspeptin |
Limbic system | Rats [64, 94] and mice [59, 94] | Mediator of olfactory function [97] |
Control of LH secretion [98, 99] | ||
Hippocampus | Rats [95, 96] | Cognition and epilepsy [96] |
Ovary | Rats [100−103] and mice [104] | Corpus luteum formation and progesterone production [101] |
Follicular development [102] | ||
Ovarian aging [103, 104] | ||
Testis | Mice [106] and humans [107] | Sperm motility and hyperactivation [107] |
Uteri | Mice [111] | Implantation [105] |
Placenta | Rats [37] and humans [35, 36, 108, 109] | Implantation [37] |
Reference numbers are shown in square brackets.