Table 3.

Gene expression results for recto-anal junction samples with fold change >2

Gene namea	Gene function	Fold change	Reference
KLRJ1 + (Ly49)	Natural killer cell receptor binding host MHC I as a mechanism of self/health recognition. Binding of the ligand results in an inhibitory signal to prevent killing of the target cell.	−3.89971	Storset et al. (2003) [27]
MARCO−	Innate immune defense. Can bind Gram-negative bacteria to stimulate clearing of the pathogen.	3.68421	Elomaa et al. (1998) [32]
CCL20−	Strongly chemotactic for lymphocytes and weakly for neutrophils.	3.33712	Mohammed et al. (2007) [22]

^a: ⁺ = upregulated; ⁻ = downregulated