Table 2.
Odds ratios (OR) and 95% confidence intervals (CI) for CVD and cause-specific CVD, for 3, 5 and 10 years prior to the index date.
| Cases With Disease: N (%) | Controls With Disease: N (%) | Crudea OR (95%CI) | Adjustedb OR (95%CI) | |
|---|---|---|---|---|
| All Cardiovascular Disease | ||||
|
| ||||
| 3 years | 516 (16.2) | 47,787 (15.0) | 1.10 (1.00–1.22) | 1.15 (1.04–1.27) |
| 5 years | 390 (12.3) | 37,181 (11.7) | 1.06 (0.95–1.18) | 1.10 (0.98–1.23) |
| 10 years | 190 (6.0) | 18,469 (5.8) | 1.03 (0.89–1.20) | 1.07 (0.92–1.25) |
|
| ||||
| Ischemic Heart Disease | ||||
|
| ||||
| 3 years | 231 (7.3) | 21,087 (6.6) | 1.11 (0.97–1.27) | 1.14 (0.99–1.31) |
| 5 years | 180 (5.7) | 16,318 (5.1) | 1.11 (0.96–1.30) | 1.15 (0.98–1.34) |
| 10 years | 85 (2.7) | 7,878 (2.5) | 1.08 (0.87–1.35) | 1.12 (0.90–1.40) |
|
| ||||
| Hypertensive Disease | ||||
|
| ||||
| 3 years | 151 (4.7) | 14,592 (4.6) | 1.04 (0.88–1.23) | 1.10 (0.90–1.31) |
| 5 years | 118 (3.7) | 10,820 (3.4) | 1.10 (0.91–1.32) | 1.17 (0.96–1.41) |
| 10 years | 56 (1.8) | 5,003 (1.6) | 1.12 (0.86–1.47) | 1.20 (0.92–1.58) |
|
| ||||
| Cerebrovascular Disease | ||||
|
| ||||
| 3 years | 98 (3.1) | 10,559 (3.3) | 0.92 (0.75–1.13) | 0.95 (0.77–1.17) |
| 5 years | 64 (2.0) | 7,760 (2.4) | 0.82 (0.64–1.05) | 0.84 (0.66–1.08) |
| 10 years | 39 (1.2) | 3,459 (1.1) | 1.13 (0.82–1.56) | 1.17 (0.85–1.62) |
|
| ||||
| Atherosclerosis | ||||
|
| ||||
| 3 years | 50 (1.6) | 3,911 (1.2) | 1.29 (0.97–1.71) | 1.36 (1.02–1.80) |
| 5 years | 33 (1.04) | 2,823 (0.89) | 1.17 (0.83–1.67) | 1.22 (0.87–1.73) |
| 10 years | 14 (0.35) | 1,126 (0.44) | 1.25 (0.73–2.11) | 1.30 (0.76–2.21) |
a
The crude analysis from conditional logistic regression includes adjustment for the matching factors
b
Additionally adjusted for socio-economic status, marital status, region of residence, diabetes, COPD and obesity