. Author manuscript; available in PMC: 2016 Dec 22.

Published in final edited form as: J Pharm Sci. 2010 Apr;99(4):2018–2031. doi: 10.1002/jps.21970

Table 2.

AUC_{0–48 h} of PP Particles from Lymph Nodes Post-SC Injection into the Dorsal Surface of the Rat Footpad

PP (nm)	AUC_{0–48 h} (mg h)/g					LPN Ratio^a	Cumulative Ratio^b
PP (nm)	LPN	LIgN	LIN	LRN	Cumulative	LPN Ratio^a	Cumulative Ratio^b
50	177.7 ± 8.69	45.86 ± 2.74	50.67 ± 3.59	11.6 ± 0.86	285.86 ± 15.87	1.9^*	2.2^*
100	140.6 ± 6.24	31.1 ± 1.86	29.53 ± 1.42	14.07 ± 1.39	215.37 ± 10.90	1.5^*	1.6^*
200	94.54 ± 4.70	12.39 ± 1.37	16.91 ± 1.80	6.84 ± 0.35	130.68 ± 8.21	1.0^*	1.0^*

n = 10; mean ± SEM.

Denotes statistical significance at p < 0.05.

Ratio of LPN AUC_{0–48 h} of PP 50 and PP 100 to LPN PP 200 particles.

Ratio of cumulative AUC_{0–48 h} of PP 50 and PP 100 to PP 200 particles.