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. Author manuscript; available in PMC: 2016 Dec 22.
Published in final edited form as: J Pharm Sci. 2010 Apr;99(4):2018–2031. doi: 10.1002/jps.21970

Table 3.

AUC0–48 h of PS Particles from Lymph Nodes Post-SC Injection into the Dorsal Surface of the Rat Footpad

PS (nm) AUC0–48 h (mg h)/g
LPN Ratioa Cumulative Ratiob
LPN LIgN LIN LRN Cumulative
60 26.99 ± 4.53 0.46 ± 0.155 1.16 ± 0.34 28.61 ± 5.33 7.4 7.1
112 22.26 ± 2.71 1.00 ± 0.39 23.26 ± 3.09 6.1 5.8
200 3.67 ± 1.56 0.36 ± 0.19 4.03 ± 1.75 1.0* 1.0*

n = 10; mean ± SEM.

*

Denotes statistical significance at p < 0.05.

a

Ratio of LPN AUC0–48 h of PS 60 and PS 112 to LPN PS 200 particles.

b

Ratio of cumulative AUC0–48 h of PS 60 and 112 to PS 200 particles.