Table 5.
AUC0–48 h of PC from Lymph Nodes Post-SC Injection into the Dorsal Surface of the Rat Footpad
PC ratio | AUC0–48 h (mg h)/g
|
LPN Ratioa | Cumulative Ratiob | ||||
---|---|---|---|---|---|---|---|
LPN | LIgN | LIN | LRN | Cumulative | |||
80:20 | 40.18 ± 5.27 | 20.48 ± 1.96 | 5.62 ± 0.71 | 11.05 ± 0.94 | 77.30 ± 8.88 | 1.0* | 1.0* |
50:50 | 96.15 ± 1.72 | 97.85 ± 6.11 | 34.63 ± 5.73 | 56.35 ± 4.75 | 284.98 ± 18.31 | 2.4* | 3.7* |
20:80 | 187.00 ± 14.18 | 302.90 ± 25.41 | 72.18 ± 8.81 | 215.60 ± 28.31 | 776.68 ± 76.71 | 4.7* | 10.1* |
n = 10; mean ± SEM.
Denotes statistical significance at p < 0.05.
Ratio of LPN AUC0–48 h of PC 80:20 and PC 50:50 to LPN PC 20:80 particles.
Ratio of cumulative AUC0–48 h of PC 80:20 and PC 50:50 to PC 20:80 particles.