. Author manuscript; available in PMC: 2016 Dec 22.

Published in final edited form as: J Pharm Sci. 2010 Apr;99(4):2018–2031. doi: 10.1002/jps.21970

Table 6.

AUC_{0–48 h} of PC and PP Particles from Serum and Lymph Nodes Post-SC Injection into the Dorsal Surface of the Rat Footpad

Particle	Serum AUC_{0–48 h} (mg h)/mL	LPN AUC_{0–48 h} (mg h)/mL	Ratio of LPN AUC_{0–48 h}^a	Cumulative node AUC_{0–48 h} (mg h)/g	Ratio of Cumulative Node AUC_{0–48 h}^a
PC 80:20	4.37 ± 0.48	40.2 ± 5.3	0.22^*	77.3 ± 8.9	0.27^*
PC 50:50	20.73 ± 1.62	96.2 ± 1.7	0.54^*	285.0 ± 18.3	1.0
PC 20:80	68.93 ± 2.61	187.0 ± 14.2	1.1	7776.7 ± 76.7	2.7^*
PP 50	6.29 ± 0.03	177.7 ± 8.7	1.0	285.9 ± 15.9	1.0

n = 10; mean ± SEM.

Denotes statistical significance at p < 0.05.

Ratio of node uptake AUC_{0–48 h} of PC particles to PP 50 particles.