Coagulant properties of Crotalus adamanteus venoms. The procoagulant and anticoagulant activities of all venoms were measured using the Sonoclot analyzer; the activated clotting time is the time that plasma remains a liquid (i.e., time in which fibrin formation begins), the clot rate is defined as the change in clot signal over time (e.g., kinetic measure of fibrin formation and clot development), and platelet function is the timing and quality of clot retraction. At least one venom significantly differed from the control for each variable; significant values are indicated by an *.