Table 4.
Univariate survival analysis
| Variable | Survival estimate % (95% Confidence interval) |
P value (log rank test) |
|---|---|---|
| AKI | 0.02 | |
| Yes | 75 (67–80) | |
| No | 94 (77–98) | |
| AKI Categories | < 0.01 | |
| R/I | 86 (78–90) | |
| F/L/E with dialysis | 36 (13–59) | |
| F/L/E without dialysis | 29 (12–48) | |
| AKI categories | 0.22 | |
| No AKI | 94 (77–98) | |
| R/I | 86 (78–90) | |
| AKI categories | <0.01 | |
| No AKI and R/I | 87 (81–91) | |
| F/L/E | 31 (17–47) | |
| AKI categories | 0.65 | |
| F/L/E with dialysis | 29 (12–48) | |
| F/L/E without dialysis | 36 (13–59) | |
| Gender | ||
| Male | 78 (69–84) | 0.98 |
| Female | 78 (67–85) | |
| Malignant indication for HSCT | 0.05 | |
| Yes | 82 (74–88) | |
| No | 72 (61–80) | |
| Stem Cell Source | ||
| Bone Marrow | 78 (68–86) | 0.07 |
| Peripheral blood | 91 (75–97) | |
| Umbilical cord | 72 (61–80) | |
| Donor Source | ||
| Autologous | 94 (77–98) | 0.04 |
| MRD | 80 (63–90) | |
| MMRD | 50 (11–80) | |
| MURD | 74 (63–82) | |
| MMURD | 75 (60–84) | |
| aGVHD (grade 3–4) | ||
| Yes | 46 (19–70) | <0.01 |
| No | 80 (73–85) | |
| VOD | ||
| Yes | 48 (26–67) | <0.01 |
| No | 81 (75–86) | |
| TBI | ||
| Yes | 75 (65–82) | 0.42 |
| No | 80 (71–86) |
Abbreviations: AKI - acute kidney injury; R/I - risk and injury; F/L/E - failure, loss and end-stage renal disease; HSCT - hematopoietic stem cell transplant; aGVHD - acute graft versus host disease; VOD - veno-occlusive disease; TBI - total body irradiation