. Author manuscript; available in PMC: 2017 Mar 1.

Published in final edited form as: Transplantation. 2017 Mar;101(3):541–547. doi: 10.1097/TP.0000000000001341

Table 1. Clinical data of tolerant kidney transplant recipients and healthy volunteers.

Patient Data	Healthy Control	Tolerant

Number of patients	11	16
Age in years [mean (range)]	48.0 (23-72)	50.6 (22-77)
Gender (Male/Female)	(9/2)	(13/3)
Recipient age at Transpl. [mean (range)]	-	32.1 (11-56)
Donor (Living/Deceased)	-	(9/7)
Time post Transpl. in years [mean (range)]	-	18.4 (10-34)
Years immunosuppression free [mean (range)]	-	6.0 (1-23)
HLA mismatches

Number of patients with:
-No mismatches	-	6
-HLA (A or B) mismatches	-	2
-HLA (A + B) mismatches	-	1
-HLA (A + DR) mismatches	-	0
-HLA (B + DR) mismatches	-	0
-HLA (A + B + DR) mismatches	-	6
-Missing data	-	1
Donor-specific antibodies (DSA)

Number of patients with:
-No DSA	-	14
-DSA Class I	-	1
-DSA Class II	-	1
-DSA Class I and II	-	0
Renal Function Parameters

Creatinine (mmols/L) [mean]	-	117.2 ± 15.6
eGFR (mL/min/1.73m²) [mean]	-	60.9 ± 16.5
Cell Count

Lymphocytes count x 10⁹ [mean±SD]	2.20 ± 0.55	2.30 ± 0.71
B-cell count x10⁹ [mean±SD]	0.43 ± 0.24	0.46 ± 0.21
Memory B-cell count x10⁹ [mean±SD]	0.12 ± 0.10	0.11 ± 0.07
Naïve B-cell count x10⁹ [mean±SD]	0.34 ± 0.23	0.38 ± 0.16
Transitional B-cell count x10⁹ [mean±SD]	0.03 ± 0.03	0.05 ± 0.02

DSA: donor-specific antibodies. eGFR: estimated glomerular filtration rate.