Table 1. Association between the clinicopathological parameters and mTOR, p-mTOR expression in 120 cases of gastric cancer.
Variable | Total patients | mTOR-positive | mTOR-negative | P value | p-mTOR-positive | p-mTOR-negative | P value | |
---|---|---|---|---|---|---|---|---|
Sex | Male | 80 | 50 | 30 | 0.60 | 46 | 34 | 0.30 |
Female | 40 | 23 | 17 | 19 | 21 | |||
Age | <60y | 49 | 21 | 28 | <0.01 | 26 | 23 | 0.84 |
>60y | 71 | 52 | 19 | 39 | 32 | |||
Tumor size | <3cm | 15 | 9 | 6 | 0.58 | 9 | 6 | 0.63 |
>3cm | 105 | 64 | 41 | 56 | 49 | |||
Differentiation | Well/moderate | 102 | 60 | 42 | 0.28 | 49 | 53 | <0.01 |
Poor | 18 | 13 | 5 | 16 | 2 | |||
Tumor location | Upper/Medium | 77 | 49 | 28 | 0.40 | 43 | 34 | 0.62 |
Low | 43 | 24 | 19 | 22 | 21 | |||
Depth of invasion | T1+T2 | 22 | 10 | 12 | 0.10 | 6 | 16 | <0.01 |
T3+T4 | 98 | 63 | 35 | 59 | 39 | |||
LN metastasis | N0 | 25 | 12 | 13 | 0.14 | 9 | 16 | 0.04 |
N1+N2+N3 | 95 | 61 | 34 | 56 | 39 | |||
Metastasis | M0 | 114 | 70 | 44 | 0.58 | 63 | 51 | 0.53 |
M1 | 6 | 3 | 3 | 2 | 4 | |||
TNM stage | I+II | 33 | 15 | 18 | 0.03 | 12 | 21 | 0.02 |
III+IV | 87 | 58 | 29 | 53 | 34 |
LN metastasis: lymph node metastasis. TNM stages are based on tumor-node-metastasis classification advocated by International Union against Cancer.