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. 2016 Dec 22;11(12):e0168085. doi: 10.1371/journal.pone.0168085

Table 1. Association between the clinicopathological parameters and mTOR, p-mTOR expression in 120 cases of gastric cancer.

Variable Total patients mTOR-positive mTOR-negative P value p-mTOR-positive p-mTOR-negative P value
Sex Male 80 50 30 0.60 46 34 0.30
Female 40 23 17 19 21
Age <60y 49 21 28 <0.01 26 23 0.84
>60y 71 52 19 39 32
Tumor size <3cm 15 9 6 0.58 9 6 0.63
>3cm 105 64 41 56 49
Differentiation Well/moderate 102 60 42 0.28 49 53 <0.01
Poor 18 13 5 16 2
Tumor location Upper/Medium 77 49 28 0.40 43 34 0.62
Low 43 24 19 22 21
Depth of invasion T1+T2 22 10 12 0.10 6 16 <0.01
T3+T4 98 63 35 59 39
LN metastasis N0 25 12 13 0.14 9 16 0.04
N1+N2+N3 95 61 34 56 39
Metastasis M0 114 70 44 0.58 63 51 0.53
M1 6 3 3 2 4
TNM stage I+II 33 15 18 0.03 12 21 0.02
III+IV 87 58 29 53 34

LN metastasis: lymph node metastasis. TNM stages are based on tumor-node-metastasis classification advocated by International Union against Cancer.