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. 2016 Dec 22;11(12):e0163089. doi: 10.1371/journal.pone.0163089

Table 2. Physician Examination Reactogenicity in the 7 Days Following Dose 1 and Dose 2 of Vaccine Pooled Data.

After Dose 1 After Dose 2
Treatment Group Treatment Group
Dose Placebo 15 μg x 2 30 μg x 1 30 μg x 2 Placebo 15 μg x 2 30 μg x 1 30 μg x 2
N 52 (%) 25 (%) 51 (%) 48 (%) 52 (%) 25 (%) 51 (%) 48 (%)
Nasal mucosal inflammation 0 0 0 0 1 (1.9) 0 0 1 (2.0)
Nasal discharge 7 (13.4) 1 (4.0) 9 (17.6) 10 (20.8) 5 (10.4) 3 (12.0) 7 (13.7) 9 (18.7)
Pharyngeal inflammation 4 (7.6) 0 1 (1.9) 1 (2.0) 1 (1.9) 0 2 (3.9) 2 (3.9)
Sinusitis 0 0 0 0 0 0 1 (1.9) 0
Cervical/ Post-auricular nodes 10 (19.2) 0 7 (13.7) 10 (20.8) 8 (15.3) 1 (4.0) 13 (25.4) 10 (20.8)
Otic inflammation 1 (1.9) 0 0 0 2 (3.8) 2 (8.0) 3 (5.8) 2 (3.9)