Table 2. Physician Examination Reactogenicity in the 7 Days Following Dose 1 and Dose 2 of Vaccine Pooled Data.
After Dose 1 | After Dose 2 | |||||||
---|---|---|---|---|---|---|---|---|
Treatment Group | Treatment Group | |||||||
Dose | Placebo | 15 μg x 2 | 30 μg x 1 | 30 μg x 2 | Placebo | 15 μg x 2 | 30 μg x 1 | 30 μg x 2 |
N | 52 (%) | 25 (%) | 51 (%) | 48 (%) | 52 (%) | 25 (%) | 51 (%) | 48 (%) |
Nasal mucosal inflammation | 0 | 0 | 0 | 0 | 1 (1.9) | 0 | 0 | 1 (2.0) |
Nasal discharge | 7 (13.4) | 1 (4.0) | 9 (17.6) | 10 (20.8) | 5 (10.4) | 3 (12.0) | 7 (13.7) | 9 (18.7) |
Pharyngeal inflammation | 4 (7.6) | 0 | 1 (1.9) | 1 (2.0) | 1 (1.9) | 0 | 2 (3.9) | 2 (3.9) |
Sinusitis | 0 | 0 | 0 | 0 | 0 | 0 | 1 (1.9) | 0 |
Cervical/ Post-auricular nodes | 10 (19.2) | 0 | 7 (13.7) | 10 (20.8) | 8 (15.3) | 1 (4.0) | 13 (25.4) | 10 (20.8) |
Otic inflammation | 1 (1.9) | 0 | 0 | 0 | 2 (3.8) | 2 (8.0) | 3 (5.8) | 2 (3.9) |