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. 2016 Dec 22;11(12):e0163089. doi: 10.1371/journal.pone.0163089

Table 6. Proportion of subjects in each treatment group meeting specified post-challenge endpoints and apparent efficacy versus Placebo (pooled data).

Treatment group
Placebo 15 μg x 2 30 μg x 1 30 μg x 2
N = 45 N = 19 N = 43 N = 38
Endpoint No. subjects affected No. subjects affected Efficacy % No. subjects affected Efficacy % No. subjects affected Efficacy %
Any Illness 21 3* 66.2 18 10.3 10 43.6
Any illness and seroconversion 20 2* 76.3 8* 58.1 3* 82.2
Systemic or lower respiratory illness and seroconversion 16 1* 85.2 5* 67.3 2* 85.2
Febrile illness and seroconversion 9 0* 100.0 3 65.1 0* 100.0

Efficacy % = 1- [Attack rate (Vaccinated group)/(Attack rate(placebo group)]

* P<0.05