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. 2016 Dec 22;11(12):e0167910. doi: 10.1371/journal.pone.0167910

Fig 4. CypD is important for metabolic control in the liver under high-fat diet conditions.

Fig 4

(A) Body weight at basal levels and following 11 wk of HFD; (B) Epididymal fat, (C) liver and (D) plantaris muscle tissue weight normalized to tibia length in HFD fed mice; (E) Blood glucose following i.p. injection of glucose and (F) area under the glucose curve under normal chow conditions; (G) Blood glucose following i.p. injection of glucose and (H) area under the glucose curve following 11 wk of HFD; (I) Blood glucose following i.p. injection of pyruvate and (J) area under the curve following 14 wk of HFD; (K) Representative Oil red O staining of liver sections from WT and LKO mice following 14 wk of HFD and (L) average lipid droplet size. ***p < 0.001 basal vs. HFD, * and **p < 0.05 WT vs. LKO; GTT and PTT n = 9–11; Oil Red O quantification n = 4.