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. 2016 Dec 22;11(12):e0168634. doi: 10.1371/journal.pone.0168634

Table 4. Impact of baseline characteristics on cardiovascular mortality.

Crude HR 95%CI Adjusted HR£ 95%CI
Sociodemographics
Female 1.70* [1.09–2.64]
Age(year) 1.07* [1.05–1.09] 1.07 [1.04–1.09]
Body mass index (kg/m2) 0.94* [0.89–0.99]
Medical history
Diabetes mellitus 1.14 [0.76–1.72]
COPD 1.03 [0.56–1.89]
Hypertension 1.29 [0.83–2.00]
Chronic renal disease 3.29* [2.07–5.24] 1.91 [1.10–3.32]
Dyslipidaemia 0.74* [0.49–1.11]
Smoker 0.74* [0.49–1.10]
Ischemic cardiomyopathy 1.34* [0.92–1.96]
Past PCI 1.00 [0.65–1.54]
Polyvascular disease 1.85* [1.26–2.71] 1.63 [1.01–2.64]
Clinical characteristics
Three-vessel disease disease 1.72* [1.14–2.59]
Supraventricular arrhythmia 1.62* [1.09–2.41]
Low LVEF §
< 12 months 2.07 [1.27–3.38] 1.87 [1.03–3.38]
≥ 12 months 0.99 [0.45–2.15] 1.24 [0.49–3.17]

Note:

* p<0.20 in bivariate analyses,

£ Cox semi proportional model for all-cause mortality including low LVEF as a time-dependent variable and using a stepwise selection process sle = 0.2 sls = 0.05 to adjust for confounders

COPD: chronic obstructive pulmonary disease,

PCI: percutaneous coronary intervention,

§ LVEF: left ventricular ejection fraction